YES! I used to be a heavy user of DXM, a few months back anyway. Well, it triggered/amplified the mental disorders that I did not know I have. Depression, bipolar disorder, anxiety, depersonalization disorder (brand new to me after DXM) etc. I ended up losing all interest in everything. Quit my job, stopped showing up to college after the first few days. Then I even lost interest in DXM. I had stopped using it but the change in my personality never went away... Every time I talk to a friend, I feel like a faceless creature who wears a different mask for every person I meet. Life was ridiculously unstable for me so I rode it to wherever it wanted to go, which was straight down. Currently I still suffer from Depersonalization disorder, as well as the rest. I even attempted suicide back in October, but weed has put me in a much better place. It has helped with everything but the anxiety and depersonalization disorder, which are AMPLIFIED by weed, unfortunately for me. Today was a particularly bad day, I apologize if my words aren't flowing well. I just feel so empty sitting here watching the clock on my computer go from 7pm, to 8pm, to 9pm, all the way until now, 1:20am. It hasn't felt real. Some days I am perfectly fine, and have no issues socializing or going to work. Other days I sit in my head for hours, questioning the universe and asking myself all these large questions. They give me anxiety and I panic from a fear of impending doom. Finally the cigarette cravings come in from not smoking for hours and break the trance. After the cigarette, I feel like me again. I'm at that point now. Sorry if this was weird, it's been a long, stressful day where I haven't been able to grasp who "I" am. I'm 19 and have fixed most of my issues but days like today still occur, albeit a lot less often. Keep your chin up, it gets better. Healing is a process, not a result. I need a cigarette right now but message me if you ever need someone to talk to. Or respond to this or something. I can still do drugs, including psychedelics, with no issues, so I can't relate there. I do know what it's like for a drug to impact one's life so much though, and can honestly say things get better. Next time you smoke weed, you should do it by yourself. You only get as high as you let yourself, so take it very slow. Talk yourself through it, constantly reminding yourself that you've done it so many times before and that you are in complete control. Go in expecting to have a nice relaxing time. Plan out your night too to avoid anxiety about what to do/where to go. Hope this helped, cheers