Lean body mass is what matters.

You might see, though, that a lot of people use their total bodyweight to estimate their macros... but this is because when people are lean, their total bodyweight is going to be pretty close to their lean body weight, and so the difference is negligible for estimation purposes. It's "easier" to calculate.

But for overweight people, this difference matters a lot more, so you'll actually need to computer your lean body mass in order for the macros to really make sense.

If you're 200 lbs at 30% bodyfat (for example), there is no way you need to eat 200g protein/day, for instance.

Estimate your bodyfat percentage (either post a pic, or use a few online metrics like the Navy Tape Test, which isn't perfect but it'll give you an idea) and from this get your lean mass weight.

For example if you are 200 lbs and have 30% bodyfat, then you'd have 140 lbs of lean mass.

With this in mind, read the science here: http://bayesianbodybuilding.com/the-myth-of-1glb-optimal-protein-intake-for-bodybuilders/

It'll explain why you see 1g/lb passed around so much. But in reality:

There is normally no advantage to consuming more than 0.82g/lb (1.8g/kg) of protein per day to preserve or build muscle once you’re past the novice level as a natural trainee. This already includes a mark-up, since most research finds no more benefits after 0.64 g/lb.

Again remember the bodyweight/lean mass thing.

So the science here suggests that you are probably fine taking (.8 x lean body mass) grams of protein per day.

For fats, (.4 x lean body mass) grams of fat per day.

Fill in the rest of your calories with carbs: ( (caloric intake - 4 x protein grams - 9 x fat grams) / 4 ) grams of carbs per day.