I really don't care about optimisation. I can't use many buttons because of a disability and this would enable me to use most of my abilities in the way I want whilst still allowing for 2 other sets of modifiers (shift and ctrl via mouse buttons). I keep getting told to use key modifiers but I've run out, that's it. I was hoping to get a straight answer without essays being told what's bad practice because I'm just trying to find clever ways to allow me to play to begin withith. I'm sorry im not playing optimally, but I physically can't and without the games ability to be modded like wow I'm relying on macros to use the multitude of abilities I get.