I'm going to share very rough summary of what I've read over the past few years across dozens of source sites, forums and articles etc.

I've read tons of people posting positive experiences with TRT and being able to ween off anxiety and depression medications specifically. These scenarios were guided by a health care professional and not illegal path or personal path going against their doctor. Never read anyone going cold turkey over night, thats not a smart move. Many were people who abused weed or even harder drugs which were a cause for the aniexty and depression or type 2 hypogonadism.

TRT and bipolar appears to be a risk because from self testimonials testosterone can amplify the mania/manic states combined with reduced impulse control. Leading some to lose control. I could imagine also if the TRT isn't balanced correctly the irregularity in estrogen and testosterone could wreak havock on depression or bouts of aggression and weight gain. I haven't seen a positive report of it with bipolar.

Remember this is not scientific whatsoever, so take it with a grain of salt against real research and your own findings.