Get her to ask her dermatologist about Accutane. Seriously. If she hasn't tried it yet because she's afraid of side effects or whatever, she needs to. If she had been on it before, you'd know - it's a daily dose for 6-12 months for a full round and she'll need to get blood taken once a month while she's on it (and NOT GET PREGNANT - very important).

It is made specifically for this situation and it's the only thing that helped when this happened to me. I finished my course of Accutane a year ago and it literally saved my life.

As for your relationship, you need to be conscious of the fact that she's going through something really traumatizing. I know it's a bummer to hang around with someone that's going through this, and compassion fatigue is a real thing, but she needs a positive force in her life. Just keep encouraging her to speak with a counselor (I know I needed one) and don't talk to her about her skin unless she comes to you first. That means no more helpful suggestions from you. She needs to listen to her doctor, and that's it. The stuff in /r/skincareaddiction doesn't cater to medical problems. What she has is a medical problem with a risk for severe facial deformity. Treating it at home isn't going to cut it.

Imagine looking in the mirror every day and not even recognizing yourself. Imagine leaving the house and realizing that suddenly, people are looking at you with pity everywhere you go. They look at your acne when they talk to you instead of your eyes. All of a sudden it's like you're some kind of leper that people avoid. You have people offering "helpful" advice about your skin all the time (as if you haven't already tried it all). On top of that, it's physically painful. ALL. THE. TIME. And you know it's going to scar, and everything you try seems to make the problem worse, and it's never going to get better. ever. because you've tried everything already and the only thing left to do is hide yourself away so that nobody has to look at you with pity ever again.

At least, that's what it felt like for me. My husband couldn't help, and I know he felt the way you're feeling now too, but I appreciated his reassurance that we'd face it together and get the problem taken care of by any means necessary.

There's a light at the end of the tunnel. I think you just need to remind her about that once in a while.